DEOXYCHOLIC ACID

PRODUCT IDENTIFICATION
CAS NO. 83-44-3

DEOXYCHOLIC ACID

EINECS NO.

201-478-5

FORMULA C24H40O4
MOL WT. 392.58

H.S. CODE

TOXICITY
SYNONYMS Cholanoic acid;
3alpha,12alpha-Dihydroxy-5beta-Cholanate; 3alpha,12alpha-Dihydroxy-5beta-Cholanoic acid; 7-Deoxycholic acid; (3alpha,5beta,12alpha)-3,12-dihydroxy-Cholan-24-oic acid;
SMILES

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

white to off-white crystalline powder

MELTING POINT 174 - 176 C
BOILING POINT

 

SPECIFIC GRAVITY  
SOLUBILITY IN WATER Soluble
pH  
VAPOR DENSITY

 

AUTOIGNITION

  

NFPA RATINGS

  

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY

Stable under ordinary conditions.

APPLICATIONS
Bile is a bitter, yellow to greenish fluid composed of glycine or taurine conjugated bile salts, cholesterol, phospholipid, bilirubin diglucuronide, and electrolytes. It is secreted by the liver and delivered to the duodenum to aid the process of digestion and fat absorption by emulsification of fat products in the upper small intestine. They play role dissolving cholesterol and accretes into lumps in the gall bladder, forming gallstones. Bile's bicarbonate constituents serves for alkalinizing the intestinal contents. Bile is responsible for as the route of excretion for hemoglobin breakdown products (bilirubin). Excretion of bile salts by liver cells and secretion of bicarbonate rich fluid by ductular cells in response to secretin are the major factors which normally determine the volume of secretion. Bile acids are liver-generated steroid carboxylic acids. The primary bile acids (cholic and chenodeoxycholic acid) are conjugated with either glycine or taurine in the form of taurocholic acid and glycocholic acid. The secondary bile acids (deoxycholic, lithocholic, and ursodeoxycholic acid) are formed from the primary bile acids by the action of intestinal bacteria. They are soluble in alcohol and acetic acid. The lithocolyl conjugates are relatively insoluble; excreted mostly in the form of sulfate esters like sulfolithocholylglycine. Most of the bile acids are reabsorbed and returned to the liver via enterohepatic circulation, where, after free acids are reconjugated, they are again excreted. 
  • Cholic Acid
  • Methyl Cholate
  • Deoxycholic Acid
  • Dehydrocholic Acid
  • Methyl Deoxycholate
  • Chenodeoxycholic Acid
  • Methyl Chenodeoxycholate
  • Sodium Glycocholate
  • Glycodeoxycholic Acid
  • Sodium Glycodeoxycholate
  • Sodium Taurocholate
  • Sodium Taurodeoxycholate
  • Ursodeoxycholic acid

Commecial bile acids' application fields include:

  • Experimental basis of cathartics, cholagogues
  • Preventing and dissolving gallstones.
  • As an intermediate for the production of corticosteroid structure drugs to treat various disorders such as pain or inflammation, brain tumors, skin diseases, and allergic reactions.
  • As detergents to emulsify biological fats.
  • Vaccine delivery system
SALES SPECIFICATION

APPEARANCE

 white to off-white crystalline powder

ASSAY

98.0% min
OPTICAL ROTATION +53° ~ +55° (C=2 in EtOH)
TRANSPORTATION
PACKING
25kgs in fiber drum
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XN , Risk Phrases: 22-36/37/38, Safety Phrases: 22-26-36/37/39
DETERGENTS IN PHARMACEUTICAL

Product

CAS RN.
Hexachlorophene 70-30-4
Taurocholic acid 81-24-3
Deoxycholic acid 83-44-3
Sarkosyl 97-78-9
Sodium Ethasulfate 126-92-1
Glycodeoxycholic acid 360-65-6
Lithocholic acid 434-13-9
Glycocholic acid 475-31-0
Taurochenodeoxycholic acid 516-35-8
Taurodeoxycholic acid 516-50-7
Taurolithocholic acid 516-90-5
Thonzonium bromide 553-08-2
Oleyl alcohol 593-47-5
Glycochenodeoxycholic acid 640-79-9
Quaternium-11 1399-80-0
N-Dodecylmorpholine 1541-81-7
Dodecyldimethylamine oxide 1643-20-5
2,4-Diacetylphloroglucinol 2161-86-6
Dodecylnicotinamide 2254-99-1
Bis(aminopropyl)laurylamine 2372-82-9
Entsufon sodium 2917-94-4
Dodecyloctaethyleneglycol monoether 3055-98-9
Polidocanol 3055-99-0
1,2-Heptanoylphosphatidylcholine 3436-45-1
1-Dodecylimidazole 4303-67-7
Hexaethyleneglycol mono-n-tetradecyl ether 5157-04-0
Dodecyltetraethylene glycol monoether 5274-68-0
Decyltetraoxyethylene glycol monoether 5703-94-6
Sodium metasilicate 6834-92-0
Cetrimonium 6899-10-1
Octyl-2-hydroxyethylsulfoxide 7305-30-8
Cetylpyridinium 7773-52-6
Olbrotol-18 8065-81-4
Laureth 4 9002-92-0
Octoxynol 9 9002-93-1
Octadecyl polyoxyethylene ether 9005-00-9
Nonidet P-40 9036-19-5
Dodecyltrimethylammonium 10182-91-9
Tetradecyltrimethylammonium 10182-92-0
Cetyldimethylbenzylammonium 10328-34-4
Tetrabutylammonium 10549-76-5
Lubrol WX 11138-41-3
Lauryl sulfobetaine 14933-08-5
Dimethyl(3-sulphonatopropyl)tetradecylammonium 14933-09-6
N,N-Dimethyl-N-(3-sulfopropyl)-1-decanaminium 15163-36-7
Stearyltrimethylammonium 15461-40-2
Deriphat 17066-08-9
n-Octylpentaoxyethylene 19327-40-3
Trideceths 24938-91-8
Tyloxapol 25301-02-4
Dodecyl polyoxyethylene sulfuric acid 26183-44-8
Polyethylene glycol decyl ethers 26183-52-8
n-Octyl-polyoxyethylene 27252-75-1
Ethylene glycol nonylphenyl ether 27986-36-3
Octyl-beta-D-glucoside 29836-26-8
Cadmium lauroyl sarcosinate 32744-72-2
Nonyltrimethylammonium 35819-23-9
Nonidet 39322-33-3
Metaupon 39388-01-7
Diisobutylnaphthalenesulfonate 52627-01-7
Poly(12-hydroxyoctadecanoic acid, oxirane) 55206-48-9
Lauramidopropylamine oxide 61792-31-2
Catamine AB 64365-16-8
Saturated alkyl C14-C18 alcohols sulfate 67016-55-1
Lubrol G 68247-89-2
Potassium coco hydrolyzed animal protein 68920-65-0
Dodecyl maltoside 69227-93-6
Mix(2-pentanone, 2-butanone) 69487-31-6
3-((3-Cholamidopropyl)dimethylammonium)-1-propanesulfonate 75621-03-3
4-(3,3-Dimethyl-1-oxotridecyl)benzenesulfonic acid 81918-89-0
3-((3-Cholamidopropyl)dimethylammonio)-2-hydroxy-1-propane sulfonate 82473-24-3
Nonanoyl-N-methylglucamide 85261-19-4
Decanoyl-N-methylglucamide 85261-20-7
Heptyl 1-thioglucoside 85618-20-8
N-Octyl-beta-D-thioglucopyranoside 85618-21-9
(11-Ferrocenylundecyl)trimethylammonium 99144-93-1
Halistanol trisulfate 103065-20-9
3-((3-Deoxycholamidopropyl)dimethylammonio)-1-propane 106679-03-2
Isononanoyl oxybenzene sulfonate 123354-92-7
Miramistin 126338-77-0
Emulkop 134092-15-2
Desintegron O 138673-63-9
Desintegron B 138673-85-5